Publications, peer reviewed:
* Corresponding author

1. Ran Wei, Arika Sugiyama, Yuta Sato, Motohiro Nozumi, Hironori Nishino, Miyuki Takahashi, Taro Saito, Kanae Ando, Mitsunori Fukuda, Mineko Tomomura, Michihiko Igarashi and Shin-ichi Hisanaga. Isoform-dependent subcellular localization of LMTK1A and LMTK1B, and their roles in axon outgrowth and spine formation. Journal of Biochemistry, in press 
   
   
2. Nishino H, Saito T, Wei R, Takano T, Tsutsumi K, Taniguchi M, Ando K,Tomomura M, Fukuda M, Hisanaga SI.The LMTK1-TBC1D9B-Rab11A Cascade Regulates Dendritic Spine Formation via Endosome Trafficking. J Neurosci. 2019 Nov 27;39(48):9491-9502.
   
3. Maruko-Otake A, Sekiya M, Iijima KM, and Ando K* Diurnal feeding pattern in adult Drosophila requires integration of the circadian clock in neurons and a non-circadian function of CLOCK protein in the digestive/metabolic tissues. (In preparation) 
   
   
4. Saito T, Oba T, Shimizu S, Asada A, Iijima KM, Ando K*. Cdk5 increases MARK4 activity and augments pathological tau accumulation and toxicity through tau phosphorylation at Ser262. Hum Mol Genet. 2019 Jun 7. pii: ddz120. doi: 10.1093/hmg/ddz120. [Epub ahead of print]  
   
   
5. Sharma G, Huo A, Kimura T, Shiozawa S, Kobayashi R, Sahara N, Ishibashi M, Ishigaki S, Saito T, Ando K, Murayama S, Hasegawa M, Sobue G, Okano H, Hisanaga SI. Tau isoform expression and phosphorylation in marmoset brains. J Biol Chem. 2019 Jun 5. pii: jbc.RA119.008415. doi: 10.1074/jbc.RA119.008415. [Epub ahead of print]
   
   
6. Takahashi M, Kobayashi Y, Ando K, Saito Y, Hisanaga SI. Cyclin-dependent kinase 5 promotes proteasomal degradation of the 5-HT1A receptor via phosphorylation.Biochem Biophys Res Commun. 2019 Mar 12;510(3):370-375. doi: 10.1016/j.bbrc.2019.01.093. Epub 2019 Jan 31.PMID: 30712943
   
   
7. Chiku T., Hayashishita M., Saito T., Oka M., Shinno K., Ohtake Y., Shimizu S., Asada A., Hisanaga SI., Iijima KM, Ando, K*. S6K/p70S6K1 protects against tau-mediated neurodegeneration by decreasing the level of tau phosphorylated at Ser262 in a Drosophila model of tauopathy. Neurobiology of Aging, 3(71):255-264, 2018
   
   
8. Sekiya M, Wang M, Fujisaki N, Sakakibara Y, Quan X, Ehrlich ME, De Jager PL, Bennett DA, Schadt EE, Gandy S, Ando K, Zhang B, Iijima KM. Integrated biology approach reveals molecular and pathological interactions among Alzheimer's Aβ42, Tau, TREM2, and TYROBP in Drosophila models. Genome Med. 2018 Mar 29;10(1):26. doi: 10.1186/s13073-018-0530-9.
   
   
9. Tuerde D, Kimura T1, Miyasaka T, Furusawa K, Shimozawa A, Hasegawa M, Ando K, and Hisanaga SI. Isoform-independent and -dependent phosphorylation of microtubule-associated protein tau in mouse brain during postnatal development. J Biol Chem. 2018 Feb 2;293(5):1781-1793. doi: 10.1074/jbc.M117.798918. Epub 2017 Dec 1.
   
   
10. Sekiya, M., Maruko-Otake, A., Hearn, S., Sakakibara, Y., Fujisaki, N., Suzuki, E., Ando, K., Iijima, K. M. EDEM Function in ERAD Protects against Chronic ER Proteinopathy and Age-Related Physiological Decline in Drosophila. Dev Cell. 2017 Jun 19;41(6):652-664.e5. doi: 10.1016/j.devcel.2017.05.019.
    
    
11. Oka,M., Naoki Fujisaki, N., Maruko-Otake, A., Ohtake, Yl., Shimizu, S., Saito, T., Hisanaga,S., Iijima,KM., and Ando, K.* (2017) Ca2+/calmodulin-dependent protein kinase II promotes neurodegeneration caused by tau phosphorylated at Ser262/356 in a transgenic Drosophila model of tauopathy. Journal of Biochemistry, 2017 Nov 1;162(5):335-342
    
    
12. Kimura, T., Hosokawa, T., Taoka, T., Tsutsumi, T., Ando, K., Ishiguro, K., Hosokawa, M., Hasegawa, M. and  Hisanaga, S. (2016) Quantitative and combinatory determination of in situ phosphorylation of tau and its FTDP-17 mutants. Scientific Reports, ep 19;6:33479. doi: 10.1038/srep33479.
    
    
13. Sharma, G., Tsutsumi, T., Saito, T., Asada, A., Ando, K., Tomomura, M., and Hisanaga, S. (2016) The kinase activity of endosomal kinase LMTK1A regulates its cellular localization and interactions with cytoskeletons. Genes to Cells, 2016 Oct;21(10):1080-1094. doi: 10.1111/gtc.12404.
    
    
14. Ando, K*, Oka, M., Ohtake, Y., Hayashishita, M., Shimizu, S., Hisanaga, S., and Iijima, K.M.* (2016) Tau phosphorylation at Alzheimer's disease-related Ser356 contributes to tau stabilization when PAR-1/MARK activity is elevated. Biochem Biophys Res Commun, Volume 478, Issue 2, Pages 929–934
    
    
15. Ando, K.*, Maruko-Otake, A., Ohtake, Y., Hayashishita, M., Sekiya, M., and Iijima, K. M. (2016) Stabilization of microtubule-unbound tau via tau phosphorylation at Ser262/356 by Par-1/MARK contributes to augmentation of AD-related phosphorylation and Aβ42-induced tau toxicity. PLoS Genetics, (12(3): e1005917. doi:10.1371/journal. pgen.1005917)

Invited review:

1. Samimi N., Asada A. and Ando K* Tau abnormalities and autophagic defects in neurodegenerative disorders; a feed-forward cycle (2019) Galen Medical Journal (accepted)

Book chapters:

1. Oka, M., Iijima, K.M. and Ando, K.* (2017) Loss of synaptic mitochondria and dementia.   Zikkennigaku, Yodosha (Japanese) Vol35, No12, p182-185, Yodosha .
   
   
2. Ando, K.*, Hearn, A., Suzuki, E., Maruko-Otake, A., Sekiya, M., and Iijima, K.M. (2015) Electron microscopy of the brains of Drosophila Models of Alzheimer’s disease.    Neuromethods, DOI 10.1007/7657_2015_75, Springer

Recent abstracts (selected)

1. Saito T., Oba, T, Shimizu, S., Iijima KM and Ando K* Cdk5 regulates MARK4 activity and synergistically augments pathological tau phosphorylation the 2018 ASCB|EMBO Meeting in San Diego, December 10, 2018
   
   
2. Chiku T., Saito T., Oka M, Asada A, Iijima KM, Takashima A and Ando K* Roles of cysteine residues in microtubule-associated protein tau in its proteostasis and toxicity in neurons. the 2018 ASCB|EMBO Meeting in San Diego, December 10, 2018
   
   
3. Oka M, Suzuki E, Hisanaga S, ijima KM, Ando K* Increasing glucose uptake in Drosophila brain neurons suppresses the reduction in ATP levels and rescues the decline in neuronal function during aging 59 Annual Drosophila Research Conference (Selected as a nanosymposium presentor)
   
   
4. Oka M., Suzuki E, Imamura H, Hisanaga S, Iijima KM and Ando K*‘Increasing glucose uptake suppresses age-dependent reductions in ATP levels in brain neurons and behavioral deficits in Drosophila’ ASCB/EMBO 2017 meeting, Philadelphia, USA • December 5, 2017
   
   
5. Oka M, Suzuki E, Hisanaga S, Iijima KM., Ando K* Mechanisms underlying age-dependent reduction in ATP levels in Drosophila brain neurons. The 4th Asia-Pacific Drosophila Research Conference, Suita, Osaka, Japan, May 10, 2017.
   
   
6. Ando K*, Maruko-Otake A, Hayashishita M, Oka M, Ohtake Y, Sekiya M, Saito T, Hisanaga S, Iijima KM. Sustained activation of CaMKII caused by depletion of mitochondria from the axon enhances tau toxicity. 46th annual meeting of Society for Neuroscience. (Selected as a nanosymposium presenter)
   
   
7. Oka,M., Suzuki, E., Hisanaga, S.-i., Iijima, KM, and Ando., K*. “Reduction in ATP levels in the axon during aging and the role of mitochondrial distribution.” 46th annual meeting of Society for Neuroscience, San Diego, USA, November 13, 2016 (Selected as a nanosymposium presenter)
   
   
8. Ando, K.*, Maruko-Otake, A., Hayashishita, M., Oka, M., Ohtake, Y., Sekiya, M., Saito, T., Hisanaga, S.-I., and Iijima, KM. Sustained activation of CaMKII caused by depletion of mitochondria from the axon enhances tau toxicity. 46th annual meeting of Society for Neuroscience, San Diego, USA, 2016, Nov 12-16 (Selected as a nanosymposium presenter)