Epigenetics is a gene expression control structure to come from the chromatin structure without the change of the DNA base sequence.
Epigenetic features, composed of multiple chromatin marks, may be maintained after cellular division.
 A large body of evidence suggests that the epigenome is inappropriately altered in many human diseases, including most cancers and lifestyle disease.
Therefore, unlike genetic mutations, the ability having reversibility to reprogram the epigenetic landscape is one of the most promising target therapies.
So, we research to engineer epigenetics during tumorigenesis and enable appropriate gene expression activity and control even exosomes secreted by tumor cells.